Interactions With Benzodiazepines and Other CNS Depressants Notify patients and caregivers that potentially deadly additive effects might arise if acetaminophen and codeine phosphate tablets are used with benzodiazepines or other CNS depressants, which includes alcohol, and never to make use of these drugs concomitantly Except supervised by a healthcare company https://codeine.store/how-long-does-codeine-take-to-work/