Abstract An association between exposure to a risk factor and age-at-onset of disease may reflect an effect on the rate of disease occurrence or an acceleration of the disease process. The difference in age-at-onset arising from case-only studies. however. may also reflect secular trends in the prevalence of exposure to the risk factor. https://www.roneverhart.com/Chateau-d-Esclans-Whispering-Angel-Rose-2020-375ml-6-Bottle-Case/